Leech Therapy
Timeless Natural Medicine

There have been many substances from leech SGS (salivary gland secretion) that have been isolated and their effects identified. There remains many substances that can be seen though electrophoresis, but remain unknown in name and function. There remains an element of mystery still to be discovered. 

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• Hirudin: Anti-coagulant, more powerful then pharmaceutical blood-thinners

• Orgalese: Brings micro-circulation back, creates and restores micro capillaries

• Calin: Inhibits blood coagulation, inhibits collagen and mediated platelet aggregation

• Destabilase: Dissolves fibrin, thrombolitic effects

• Bdellins: Anti-inflammatory 

• Eglins: Anti-inflammatory

• Hyaluronidase: Antibiotic, increases viscosity

• Chloromycetyn: Antibiotic effect

• Tryptase Inhibitor: Inhibits proteolitic enzymes of host mast cells

• Factor Xa Inhibitor: Inhibits the coagulation of factor XA by forming equimolar complexes

• Compliment Inhibitors: Replaces natural compliment inhibitors if they are deficient

• Carboxypeptidase A Inhibitors: Increases the inflow of blood

• Histamine like substances: Vasodilator, increases the inflow of blood at the bite site

• Acetycholine: Vasodilator

• Anesthetic

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How it Works With Heart health

 

With all our knowledge on healthy lifestyle and heart health the number one killer still remains cardiovascular disease and thrombosis remains a significant factor in causing the heart disease. It is also well documented that thrombin is the primary enzyme responsible for coronary thrombosis or the clogging of the arteries.

 

Let's take a closer look at some specifics of heart health and compare the use of natural Hirudin with it’s closest competition for venous congestion and complications which is heparin.

 

Factors related to the clotting process:

 

Factor Xa converts the prothrombin zymogen to its active form thrombin. Thrombin converts fibrinogen to fibrin and triggers the conversion of fibrin to cross-linked fibrin, and activates coagulation cofactors V and VIII. Once fibrin forms, thrombin attaches to it and amplifies its own generation 300 – 500 fold. Since this is the process that leads to the need for blood thinners for many problems, it has been the position of the medical world to focus on the direct inhibition of thrombin which is the main component in the process.

 

• Leech salivary gland secretion is the best naturally occurring thrombin and Factor Xa inhibitor known.

• Hirudin is a 3 to 5 times stronger anticoagulant than heparin.

• Hirudin does not require any cofactors to be effective while heparin requires plasma cofactor antithrombin III in order to work, resulting in the progressive depletion of natural anticoagulants.

• Hirudin does not consume antithrombin III (better for those with antithrombin III deficiency) no need for antithrombin III replacement therapy.

• Hirudin is not inactivated by antiheparin proteins, whereas the use of heparin can lead to heparin resistance in patients with inflammatory or malignant disorders.

• Hirudin has no direct effects on platelet or endothelial cells, whereas heparin may contribute to associated risk of bleeding. Heparin use runs the risk of developing the side effect heparin induced thrombocytopenia.

• Heparin can not inactivate fibrin-bound thrombin (thrombin already attached to fibrin).

• Hirudin also binds non specifically to other agents in the blood, not only thrombin.

• Hirudin is a direct active-site inhibitor with the ability to bind to clot-bound thrombin, it does not require access to the heparin receptor.

• Heparin is an indirect inhibitor and relies only on attaching to one of four receptors on thrombin, the heparin receptor. When thrombin binds to fibrin, the heparin site is inaccessible and heparin is useless.

• Platelet Aggregation which is the clumping together of platelets in the blood, is part of the sequence of events leading to the formation of a thrombus (clot), and is also more effectively treated using hirudotherapy (SGS) over heparin or other modern medicines.